Tuesday, 22 July 2008

Breast Carcinoma with Basal Phenotype: Mammographic Findings

Breast Carcinoma with Basal Phenotype: Mammographic Findings
Angela A. Luck, Andrew J. Evans, Jonathan J. James, Emad A. Rakha, E. Claire Paish, Andrew R. Green, and Ian O. Ellis
AJR 2008;191:346-351

Link to Journal

Forty-one (12%) of the screening-detected tumors had basal phenotypic expression, and these were compared with 309 (88%) nonbasal tumors. Basal-phenotype tumors were significantly more likely to manifest as an ill-defined mass (basal phenotype, 25 [61%] of 41 tumors; nonbasal phenotype, 75 [24%] of 309 tumors; p < p =" 0.019).">

Screening-detected breast tumors with a basal phenotype have a mammographic appearance different from that of nonbasal tumors. This finding may explain the good prognostic value of mammographic spiculation reported in previous studies.

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