Blinded Comparison of Computer-Aided Detection with Human Second Reading in Screening Mammography
Dianne Georgian-Smith, Richard H. Moore, Elkan Halpern, Eren D. Yeh, Elizabeth A. Rafferty, Helen Anne D'Alessandro, Mary Staffa, Deborah A. Hall, Kathleen A. McCarthy, and Daniel B. Kopans
AJR 2007;189:1135-1141
http://www.ajronline.org/cgi/content/abstract/189/5/1135
A human second reader or the use of a CAD system can increase the
cancer detection rate, but we found no statistical difference between the two because of the
small sample size. A possible benefit from a human second reader is that CAD systems can only point to possible abnormalities, whereas a human must determine the significance of the finding. Having two humans review a study may increase detection rates due to interpreter - hence - perceptual variability and not just increased detection.
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