Comparison of Computer-Aided Detection - Commentary

Blinded Comparison of Computer-Aided Detection with Human Second Reading in Screening Mammography: The Importance of the Question and the Critical Numbers Game
Rachel F. Brem
AJR 2007;189:1142-1144

http://www.ajronline.org/cgi/content/full/189/5/1142

Commentary from Rachel Brem praising the study, but pointing out the need for a larger study with this design to increase the statistical power, and for more research into why CAD picks up certain types of cancer, and human readers pick up another.

Blinded Comparison of Computer-Aided Detection with Human Second Reading

Blinded Comparison of Computer-Aided Detection with Human Second Reading in Screening Mammography
Dianne Georgian-Smith, Richard H. Moore, Elkan Halpern, Eren D. Yeh, Elizabeth A. Rafferty, Helen Anne D'Alessandro, Mary Staffa, Deborah A. Hall, Kathleen A. McCarthy, and Daniel B. Kopans
AJR 2007;189:1135-1141

http://www.ajronline.org/cgi/content/abstract/189/5/1135

A human second reader or the use of a CAD system can increase the
cancer detection rate, but we found no statistical difference between the two because of the
small sample size. A possible benefit from a human second reader is that CAD systems can only point to possible abnormalities, whereas a human must determine the significance of the finding. Having two humans review a study may increase detection rates due to interpreter - hence - perceptual variability and not just increased detection.

Stereotactic Breast Biopsy: Comparison of Histologic Underestimation Rates

Stereotactic Breast Biopsy: Comparison of Histologic Underestimation Rates with 11- and 9-Gauge Vacuum-Assisted Breast Biopsy
Ana P. Lourenco, Martha B. Mainiero, Elizabeth Lazarus, Dilip Giri, and Barbara Schepps
AJR 2007;189:275-279

http://www.ajronline.org/cgi/content/abstract/189/5/W275

Usual problems with ADH and underestimation of DCIS/invasive cancer. Comparison of 2 different gauge needles. Increasing size to 9 -guage gave no improvement in diagnostic accuracy.
There was no statistically significant difference between 11-gauge biopsy
and 9-gauge biopsy in underestimation of atypical ductal hyperplasia and ductal carcinoma in situ.

Full-Field Digital Versus Screen-Film Mammography: Comparative Accuracy in Concurrent Screening Cohorts

Full-Field Digital Versus Screen-Film Mammography: Comparative Accuracy in Concurrent Screening Cohorts
Marco Rosselli Del Turco, Paola Mantellini, Stefano Ciatto, Rita Bonardi, Francesca Martinelli, Barbara Lazzari, Nehmat Houssami
AJR 2007; 189:860-866

http://www.ajronline.org/cgi/content/full/189/4/860

Digital mammography may be more effective than screen-film mammography in contemporary screening practice in mobile units. The data indicate that digital mammography depicts more tumors than does screen-film mammography, especially lesions seen as microcalcifications. The potential association with improved outcome warrants further study

Imaging–Histologic Discordance at MRI-Guided 9-Gauge Vacuum-Assisted Breast Biopsy

Imaging–Histologic Discordance at MRI-Guided 9-Gauge Vacuum-Assisted Breast Biopsy
Jung-Min Lee, Jennifer B. Kaplan, Melissa P. Murray, Lia Bartella, Elizabeth A. Morris, Sandra Joo, D. David Dershaw, Laura Liberman
AJR 2007; 189:852-859

http://www.ajronline.org/cgi/content/full/189/4/852

Imaging–histologic discordance was found in 7% of lesions that had MRI-guided vacuum-assisted biopsy. Among discordant lesions, surgical excision revealed cancer in 30%. Imaging–histologic correlation is essential after MRI-guided vacuum-assisted biopsy to avoid delay in the diagnosis of breast cancer

Digital Breast Tomosynthesis: Initial Experience in 98 Women with Abnormal Digital Screening Mammography

Digital Breast Tomosynthesis: Initial Experience in 98 Women with Abnormal Digital Screening Mammography
Steven P. Poplack, Tor D. Tosteson, Christine A. Kogel, Helene M. Nagy
AJR 2007; 189:616-623

http://www.ajronline.org/cgi/content/full/189/3/616

Subjectively, tomosynthesis has comparable or superior image quality to that of film-screen mammography in the diagnostic setting, and it has the potential to decrease the recall rate when used adjunctively with digital screening mammography

Commentary. Tomosynthesis: Potential Clinical Role in Breast Imaging

Commentary: Tomosynthesis: Potential Clinical Role in Breast Imaging
David Gur
AJR 2007; 189:614-615
http://www.ajronline.org/cgi/content/full/189/3/614

Breast Imaging: Current Utilization, Trends, and Implications

Breast Imaging: Current Utilization, Trends, and Implications
Lawrence W. Bassett
AJR 2007; 189:612-613
http://www.ajronline.org/cgi/content/full/189/3/612

His personal story

Underestimation of DCIS at MRI-Guided Vacuum-Assisted Breast Biopsy

Underestimation of DCIS at MRI-Guided Vacuum-Assisted Breast Biopsy
Jung-min Lee, Jennifer B. Kaplan, Melissa P. Murray, Marzena Mazur-Grbec, Tade Tadic, Damir Stimac, and Laura Liberman
AJR 2007;189:468-474
http://www.ajronline.org/cgi/content/abstract/189/2/468