Thursday, 23 October 2008

Malignant-Appearing Microcalcifications at the Lumpectomy Site with the Use of FloSeal Hemostatic Sealant

Malignant-Appearing Microcalcifications at the Lumpectomy Site with the Use of FloSeal Hemostatic Sealant
Amy Henkel, Richard A. Cooper, Kathleen A. Ward, Davide Bova, and Katharine Yao
AJR 2008;191:1371-1373

Link to Journal

Application of FloSeal hemostatic sealant in the lumpectomy cavity results in benign mammographic microcalcifications that could be misinterpreted as malignant

Underestimation of Atypical Ductal Hyperplasia at Sonographically Guided Core Biopsy of the Breast

Underestimation of Atypical Ductal Hyperplasia at Sonographically Guided Core Biopsy of the Breast
Mijung Jang, Nariya Cho, Woo Kyung Moon, Jeong Seon Park, Min Hyun Seong, and In Ae Park
AJR 2008;191:1347-135

Link to Journal

For sonographically guided core biopsy of the breast, the rate of underestimation of ADH was 48%. This rate was lower for lesions evaluated with 11-gauge vacuum-assisted biopsy (22%) than for those evaluated with 14-gauge automated gun biopsy (65%). This finding was particularly true of smaller lesions (≤ 2.0 cm) and for lesions of the mass-only type

Radiofrequency Identification Tags for Preoperative Tumor Localization: Proof of Concept

Radiofrequency Identification Tags for Preoperative Tumor Localization: Proof of Concept
Joshua J. Reicher, Murray A. Reicher, Mariam Thomas, and Robert Petcavich
AJR 2008;191:1359-1365

Link to Journal

This is an interesting proof of concept study from UCLA showing how you could potentially use everyday tracker devices used for stock inventopry to identify and mark lesions in the breast. The combination of RFID tags and a new handheld RFID detector shows promise for preoperative imaging-guided tumor localization

Variable Appearances of Fat Necrosis on Breast MRI

Variable Appearances of Fat Necrosis on Breast MRI
Caroline P. Daly, Barbara Jaeger, and David S. Sill
AJR 2008;191:1374-1380

Link to Journal

Fat necrosis may mimic malignancy with varying appearances on MRI. Suspicious morphologic and kinetic features may be present, necessitating biopsy to exclude new or recurrent breast cancer

Contrast-Enhanced MR Mammography: Improved Lesion Detection and Differentiation with Gadobenate Dimeglumine

Contrast-Enhanced MR Mammography: Improved Lesion Detection and Differentiation with Gadobenate Dimeglumine
Federica Pediconi, Carlo Catalano, Simona Padula, Antonella Roselli, Valeria Dominelli, Sabrina Cagioli, Miles A. Kirchin, Gianpaolo Pirovano, and Roberto Passariello
AJR 2008;191:1339-1346

Link to Journal

Lesion detection and malignant–benign differentiation is significantly better with 0.1 mmol/kg gadobenate dimeglumine than 0.1 mmol/kg gadopentetate dimeglumine

Dynamic Contrast-Enhanced MRI for Prediction of Breast Cancer Response to Neoadjuvant Chemotherapy: Initial Results

Dynamic Contrast-Enhanced MRI for Prediction of Breast Cancer Response to Neoadjuvant Chemotherapy: Initial Results
Claudette E. Loo, H. Jelle Teertstra, Sjoerd Rodenhuis, Marc J. van de Vijver, Juliane Hannemann, Saar H. Muller, Marie-Jeanne Vrancken Peeters, and Kenneth G. A. Gilhuijs
AJR 2008;191:1331-1338

Link to Journal

Reduction of less than 25% in largest diameter of late enhancement during neoadjuvant chemotherapy shows the potential to predict residual tumor after therapy with high specificity.
This paper however continues the trend to measure anatomical dimensions, which are late responses to chemotherapy, and do not give the early feedback about neoadjuvant response

Dual-Time-Point 18F-FDG PET/CT Versus Dynamic Breast MRI of Suspicious Breast Lesions

Dual-Time-Point 18F-FDG PET/CT Versus Dynamic Breast MRI of Suspicious Breast Lesions
Massimo Imbriaco, Maria Grazia Caprio, Gennaro Limite, Leonardo Pace, Teresa De Falco, Ermanno Capuano, and Marco Salvatore
AJR 2008;191:1323-1330

Link to journal

A dual time point improves PET/CT accuracy in patients with a suspected breast malignancy over single-time-point PET/CT. On PET/CT, FDG is increasingly taken up over time in breast tumors; conversely, benign lesions show a decrease in FDG uptake over time. These changes in SUV might represent a reliable parameter that can be used to differentiate benign from malignant lesions of the breast on PET/CT examination

Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis

Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis
Pari V. Pandharipande, Mukesh G. Harisinghani, Elissa M. Ozanne, Michelle C. Specht, Chin Hur, Janie M. Lee, and G. Scott Gazelle
AJR 2008;191:1308-1319

Link to Journal

From a cost-effectiveness perspective, MR lymphangiography strategies for axillary staging of early breast cancer are preferred over SLN biopsy alone. The sensitivity of MR lymphangiography is a critical determinant of the cost-effectiveness of MR lymphangiography strategies and merits further investigation in the care of patients with early breast cancer